KAT7 Rabbit Monoclonal antibody

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Catalog Number:MABN03055
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:Recombinant protein of human KAT7/Hbo1/MYST2
Reactivity:Human
Applications:WB 1:500-1:1000,IHC 1:50-1:100,ICC/IF 1:50-1:200,IP 1:20-1:50
Molecular Weight:Calculated MW: 71 kDa; Observed MW: 71 kDa
Purification:Affinity Purified
Form:Liquid
Synonyms:HBO1; HBOA; MYST2; ZC2HC7

Applications

WB 1:500-1:1000,IHC 1:50-1:100,ICC/IF 1:50-1:200,IP 1:20-1:50

Immunogen

Recombinant protein of human KAT7/Hbo1/MYST2

Target Background

Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Through chromatin acetylation it may regulate DNA replication and act as a coactivator of TP53-dependent transcription. Specifically represses AR-mediated transcription.

Synonyms:HBO1; HBOA; MYST2; ZC2HC7

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

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