Immunological Sciences

KAT8 / MYST1 / MOF (9E16) Rabbit Monoclonal Antibody

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Catalog Number:MABN12907
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human MOF
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:2000,IHC 1:200-1:500,ICC/IF 1:500-1:2000,FC 1:100-1:200,IP 1:100-1:200
Molecular Weight:52kDa
Purification:Affinity purification
Form:Liquid
Synonyms:hMOF; MOF; MOZ; MYST1; SAS2; SAS3; YBF2; YBF2/SAS3; ZC2HC8;

Applications

WB 1:500-1:2000,IHC 1:200-1:500,ICC/IF 1:500-1:2000,FC 1:100-1:200,IP 1:100-1:200

Immunogen

A synthetic peptide of human MOF

Target Background

Histone acetyltransferase which may be involved in transcriptional activation. May influence the function of ATM. Histone acetyltransferase which may be involved in transcriptional activation (PubMed:12397079, PubMed:22020126). May influence the function of ATM (PubMed:15923642). As part of the MSL complex it is involved in acetylation of nucleosomal histone H4 producing specifically H4K16ac (PubMed:16227571, PubMed:16543150, PubMed:21217699, PubMed:22547026, PubMed:22020126). As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues (PubMed:20018852, PubMed:22547026). That activity is less specific than the one of the MSL complex (PubMed:20018852, PubMed:22547026). Can also acetylate TP53/p53 at 'Lys-120'.

Synonyms:hMOF; MOF; MOZ; MYST1; SAS2; SAS3; YBF2; YBF2/SAS3; ZC2HC8;

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

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