KCNH2 Rabbit Polyclonal Antibody

Western blot analysis of various lysates using KCNH2 Rabbit Polyclonal Antibody at 1:500 dilution.

Western blot analysis of various lysates using KCNH2 Rabbit Polyclonal Antibody at 1:500 dilution.

Catalog Number:AB2968
Conjugate:Unconjugated
Size:100 ug
Host:Rabbit
Isotype:IgG
Immunogen:Synthetic peptide. This information is considered to be commercially sensitive.
Reactivity:Human, Mouse
Applications:WB 1:500 - 1:2000; IHC-P 1:50 - 1:200; ELISA Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.; IF-P 1:50 - 1:200
Molecular Weight:148kDa
Purification:Affinity purification
Form:Liquid
Synonyms:ERG1; HERG; LQT2; SQT1; ERG-1; H-ERG; HERG1; Kv11.1; KCNH2

This gene encodes a component of a voltage-activated potassium channel found in cardiac muscle, nerve cells, and microglia. Four copies of this protein interact with one copy of the KCNE2 protein to form a functional potassium channel. Mutations in this gene can cause long QT syndrome type 2 (LQT2). Transcript variants encoding distinct isoforms have been identified.

Applications

WB 1:500 - 1:2000; IHC-P 1:50 - 1:200; ELISA Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.; IF-P 1:50 - 1:200

Immunogen

Synthetic peptide. This information is considered to be commercially sensitive.

Target Background

This gene encodes a component of a voltage-activated potassium channel found in cardiac muscle, nerve cells, and microglia. Four copies of this protein interact with one copy of the KCNE2 protein to form a functional potassium channel. Mutations in this gene can cause long QT syndrome type 2 (LQT2). Transcript variants encoding distinct isoforms have been identified.

Synonyms:ERG1; HERG; LQT2; SQT1; ERG-1; H-ERG; HERG1; Kv11.1; KCNH2

Storage

Store at -20℃. Avoid freeze / thaw cycles.

Buffer

PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.

Western blot analysis of various lysates using KCNH2 Rabbit Polyclonal Antibody at 1:500 dilution.

Immunohistochemistry analysis of paraffin-embedded Human lung cancer using KCNH2 Rabbit Polyclonal Antibody at dilution of 1:100 (40x lens). Microwave antigen retrieval performed with 0.01M PBS Buffer (pH 7.2) prior to IHC staining.

Immunohistochemistry analysis of paraffin-embedded Human colon carcinoma using KCNH2 Rabbit Polyclonal Antibody at dilution of 1:100 (40x lens). Microwave antigen retrieval performed with 0.01M PBS Buffer (pH 7.2) prior to IHC staining.

Immunohistochemistry analysis of paraffin-embedded Human breast cancer using KCNH2 Rabbit Polyclonal Antibody at dilution of 1:100 (40x lens). Microwave antigen retrieval performed with 0.01M PBS Buffer (pH 7.2) prior to IHC staining.

Immunofluorescence analysis of Mouse kidney tissue using KCNH2 Rabbit Polyclonal Antibody at a dilution of 1:200 (40x lens). Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining. High pressure antigen retrieval performed with 0.01M Citrate Buffer (pH 6.0) prior to IF staining.

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