KDM4B Rabbit Monoclonal Antibody

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Catalog Number:MABN85733
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human KDM4B/JMJD2B
Reactivity:Human
Applications:WB 1:500-1:1000,IHC 1:50-1:100,ICC 1:50-1:200
Molecular Weight:Calculated MW: 122 kDa; Observed MW: 150 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:KDM4B; JHDM3B; JMJD2B; KIAA0876; Lysine-specific demethylase 4B; JmjC domain-containing histone demethylation protein 3B; Jumonji domain-containing protein 2B

Applications

WB 1:500-1:1000,IHC 1:50-1:100,ICC 1:50-1:200

Immunogen

A synthetic peptide of human KDM4B/JMJD2B

Target Background

Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate.

Synonyms:KDM4B; JHDM3B; JMJD2B; KIAA0876; Lysine-specific demethylase 4B; JmjC domain-containing histone demethylation protein 3B; Jumonji domain-containing protein 2B

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.

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