Immunological Sciences

Ki 67(4A8)Mouse Monoclonal Antibody

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Catalog Number:MABN12993
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:IgG
Clone:Monoclonal
Immunogen:Synthetic Peptide of Ki 67
Reactivity:Human
Applications:WB 1:500-1:2000,IHC 1:100-1:200,ICC/IF 1:50-1:200
Purification:Affinity purification
Form:Liquid
Synonyms:MKI67; Antigen KI-67

Applications

WB 1:500-1:2000,IHC 1:100-1:200,ICC/IF 1:50-1:200

Immunogen

Synthetic Peptide of Ki 67

Target Background

This gene encodes a nuclear protein that is associated with and may be necessary for cellular proliferation. Alternatively spliced transcript variants have been described. A related pseudogene exists on chromosome X. [provided by RefSeq, Mar 2009],developmental stage:Expression of this antigen occurs preferentially during late G1, S, G2 and M phases of the cell cycle, while in cells in G0 phase the antigen cannot be detected.,function:Thought to be required for maintaining cell proliferation.,online information:Ki-67 entry,similarity:Contains 1 FHA domain.,subcellular location:Predominantly localized in the G1 phase in the perinucleolar region, in the later phases it is also detected throughout the nuclear interior, being predominantly localized in the nuclear matrix. In mitosis, it is present on all chromosomes.,subunit:Interacts with KIF15. Binds through the FHA domain to MKI67IP.,

Synonyms:MKI67; Antigen KI-67

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

PBS, pH 7.4, containing 0.5%BSA, 0.02% New type preservative N as Preservative and 50% Glycerol.

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