Immunological Sciences

KI67 Mouse Monoclonal Antibody

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Catalog Number:MABN80747
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:Mouse IgG2b
Clone:Monoclonal
Immunogen:Synthetic peptide corresponding to aa (CEDLAGFKELFQTPG) of human KI67, conjugated to KLH.
Reactivity:Human,Mouse,Rat,Rabbit,Monkey
Applications:IHC 1:100-1:500,ICC 1:50-1:500,ELISA 1:5000-1:20000
Molecular Weight:358kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:KIA; Ki-67; MKI67

Applications

IHC 1:100-1:500,ICC 1:50-1:500,ELISA 1:5000-1:20000

Immunogen

Synthetic peptide corresponding to aa (CEDLAGFKELFQTPG) of human KI67, conjugated to KLH.

Target Background

Ki67, also known as MKI67, it is the prototypic cell cycle related nuclear protein, expressed by proliferating cells in all phases of the active cell cycle (G1, S, G2 and M phase). It is absent in resting (G0) cells. Ki67 antibodies are useful in establishing the cell growing fraction in neoplasms (immunohistochemically quantified by determining the number of Ki67 positive cells among the total number of resting cells = Ki67 index). In neoplastic tissues the prognostic value is comparable to the tritiated thymidine labelling index. The correlation between low Ki67 index and histologically low grade tumours is strong. Ki67 is routinely used as a neuronal marker of cell cycling and proliferation.

Synonyms:KIA; Ki-67; MKI67

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide,0.5%BSA and 50% glycerol.

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