Immunological Sciences

Kir2.1 (17H9) Rabbit Monoclonal Antibody

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Catalog Number:MABN13025
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human Kir2.1
Reactivity:Human,Mouse,Rat
Applications:WB 1:1000-1:5000,IHC 1:200-1:500,ICC/IF 1:100-1:200
Molecular Weight:48kDa
Purification:Affinity purification
Form:Liquid
Synonyms:KCNJ2; ATFB9; HHBIRK1; IRK1; KIR2.1; LQT7; HIRK1; IRK-1; HHIRK1; SQT3;

Applications

WB 1:1000-1:5000,IHC 1:200-1:500,ICC/IF 1:100-1:200

Immunogen

A synthetic peptide of human Kir2.1

Target Background

Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium or cesium.

Synonyms:KCNJ2; ATFB9; HHBIRK1; IRK1; KIR2.1; LQT7; HIRK1; IRK-1; HHIRK1; SQT3;

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

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