Immunological Sciences

KLF10 (16L10) Rabbit Monoclonal Antibody

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Catalog Number:MABN13052
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human KLF10
Reactivity:Human,Mouse,Rat
Applications:WB 1:1000-1:5000
Molecular Weight:53kDa
Purification:Affinity purification
Form:Liquid
Synonyms:EGR alpha; EGRA; Egral; EGRalpha; Gdnfif; KLF10; mGIF; TIEG; TIEG1;

Applications

WB 1:1000-1:5000

Immunogen

A synthetic peptide of human KLF10

Target Background

Transcriptional repressor which binds to the consensus sequence 5'-GGTGTG-3'. Plays a role in the regulation of the circadian clock; binds to the GC box sequence in the promoter of the core clock component ARTNL/BMAL1 and represses its transcriptional activity. Transcriptional repressor which binds to the consensus sequence 5'-GGTGTG-3'. Plays a role in the regulation of the circadian clock; binds to the GC box sequence in the promoter of the core clock component ARTNL/BMAL1 and represses its transcriptional activity. Regulates the circadian expression of genes involved in lipogenesis, gluconeogenesis, and glycolysis in the liver. Represses the expression of PCK2, a rate-limiting step enzyme of gluconeogenesis (By similarity). May play a role in the cell cycle regulation.

Synonyms:EGR alpha; EGRA; Egral; EGRalpha; Gdnfif; KLF10; mGIF; TIEG; TIEG1;

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

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