Immunological Sciences

KLF4 Mouse Monoclonal Antibody

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Catalog Number:MABN86112
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:Mouse IgG1
Clone:Monoclonal
Immunogen:This KLF4 antibody is generated from a mouse immunized with a recombinant protein from the human region of human KLF4.
Reactivity:Human, Mouse
Applications:WB 1:500-1:1000
Molecular Weight:54.7kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:Krueppel-like factor 4, Epithelial zinc finger protein EZF, Gut-enriched krueppel-like factor, KLF4, EZF, GKLF

Applications

WB 1:500-1:1000

Immunogen

This KLF4 antibody is generated from a mouse immunized with a recombinant protein from the human region of human KLF4.

Target Background

Transcription factor; can act both as activator and as repressor. Binds the 5'-CACCC-3' core sequence. Binds to the promoter region of its own gene and can activate its own transcription. Regulates the expression of key transcription factors during embryonic development. Plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. Contributes to the down-regulation of p53/TP53 transcription.

Synonyms:Krueppel-like factor 4, Epithelial zinc finger protein EZF, Gut-enriched krueppel-like factor, KLF4, EZF, GKLF

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide.

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