KLF4 Rabbit Monoclonal Antibody

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Catalog Number:MABN86216
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:Recombinant protein of human KLF4
Reactivity:Human
Applications:WB 1:500-1:2000,IHC 1:200-1:2000,ICC/IF 1:100-1:200,FC 1:20-1:50,IP 1:20-1:50
Molecular Weight:Calculated MW:54 kDa; Observed MW:54 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:EZF; GKLF

Applications

WB 1:500-1:2000,IHC 1:200-1:2000,ICC/IF 1:100-1:200,FC 1:20-1:50,IP 1:20-1:50

Immunogen

Recombinant protein of human KLF4

Target Background

This gene encodes a protein that belongs to the Kruppel family of transcription factors. The encoded zinc finger protein is required for normal development of the barrier function of skin. The encoded protein is thought to control the G1-to-S transition of the cell cycle following DNA damage by mediating the tumor suppressor gene p53. Mice lacking this gene have a normal appearance but lose weight rapidly, and die shortly after birth due to fluid evaporation resulting from compromised epidermal barrier function. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2015]

Synonyms:EZF; GKLF

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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