KMT1B/SUV39H2 Rabbit Monoclonal Antibody

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Catalog Number:MABN84283
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthesized peptide derived from human KMT1B
Reactivity:Human,Mouse,Rat
Applications:WB 1:1000-1:2000,IHC 1:100-1:200,IP 1:20-1:50
Molecular Weight:47 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:H3 K9 HMTase 2; KMT1B; Su(var)3 9 homolog 2; Suv39h2;;KMT1B

Applications

WB 1:1000-1:2000,IHC 1:100-1:200,IP 1:20-1:50

Immunogen

A synthesized peptide derived from human KMT1B

Target Background

Histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3 using monomethylated H3 'Lys-9' as substrate. H3 'Lys-9' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Mainly functions in heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin at pericentric and telomere regions.

Synonyms:H3 K9 HMTase 2; KMT1B; Su(var)3 9 homolog 2; Suv39h2;;KMT1B

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

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