[KO Validated] CRMP2/DPYSL2 Rabbit mAb
Western blot analysis of extracts of various cell lines, using CRMP2/DPYSL2 Rabbit mAb at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit .Exposure time: 3s.
| Catalog Number: | AB4411 |
| Conjugate: | Unconjugated |
| Size: | 100 ug |
| Concentration: | 1mg/ml |
| Host: | Rabbit |
| Isotype: | IgG |
| Clone: | ARC1123 |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 473-572 of human CRMP2/DPYSL2 (Q16555). |
| Reactivity: | Human,Mouse,Rat |
| Applications: | WB,1:500 - 1:5000 IF/ICC,1:50 - 1:200 |
| Molecular Weight: | 62kDa |
| Purification: | Affinity purification |
| Form: | liquid |
| Synonyms: | None |
This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Applications
WB,1:500 - 1:5000 IF/ICC,1:50 - 1:200
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 473-572 of human CRMP2/DPYSL2 (Q16555).
