[KO Validated] SQSTM1/p62 Rabbit mAb

Western blot analysis of lysates from wild type (WT) and SQSTM1/p62 knockout (KO) 293T cells using [KO Validated] SQSTM1/p62 Rabbit mAb at 1:20000 dilution incubated overnight at 4℃.

Western blot analysis of lysates from wild type (WT) and SQSTM1/p62 knockout (KO) 293T cells using [KO Validated] SQSTM1/p62 Rabbit mAb at 1:20000 dilution incubated overnight at 4℃.

Catalog Number:MAB28886
Conjugate:Unconjugated
Size:100 ug
Host:Rabbit
Isotype:IgG
Clone:D1Q5S
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Reactivity:Human
Applications:WB,IHC-P,IF/ICC,IP,ELISA
Molecular Weight:62 kDa
Purification:Affinity purification
Form:Liquid
Synonyms:p60; p62; A170; DMRV; OSIL; PDB3; ZIP3; p62B; EBIAP; NADGP; FTDALS3

This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.

Applications

WB,IHC-P,IF/ICC,IP,ELISA

Immunogen

Recombinant protein (or fragment).This information is considered to be commercially sensitive.

Target Background

This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.

Synonyms:p60; p62; A170; DMRV; OSIL; PDB3; ZIP3; p62B; EBIAP; NADGP; FTDALS3

Storage

Store at -20℃. Avoid freeze / thaw cycles.

Buffer

PBS with 0.09% Sodium azide,0.05% BSA,50% glycerol,pH7.3.

Western blot analysis of lysates from wild type (WT) and SQSTM1/p62 knockout (KO) 293T cells using [KO Validated] SQSTM1/p62 Rabbit mAb at 1:20000 dilution incubated overnight at 4℃.

Western blot analysis of lysates from Hep G2 cells using [KO Validated] SQSTM1/p62 Rabbit mAb at 1:20000 dilution incubated overnight at 4℃.

Immunohistochemistry analysis of paraffin-embedded Human breast cancer tissue using [KO Validated] SQSTM1/p62 Rabbit mAb at a dilution of 1:5000 (40x lens).

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