KU70

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Catalog Number:AB-82007
Size:100μg
Concentration:1mg/ml
Host:Rb
Isotype:IgG
Clone:POLY
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 500-600 of human KU70.
Reactivity:Hu,Ms,Rt
Applications:Western Blot: 1:500 -1:2000 Immunohistochemistry: 1:50 -1:200 Immunofluorescence: 1:50 - 1:200
Molecular Weight:70kDa
Purification:Aff. Pur.
Form:Liquid
Synonyms:XRCC6; CTC75; CTCBF; G22P1; KU70; ML8; TLAA; X -ray repair cross complementing 6

Applications

Western Blot: 1:500 -1:2000 Immunohistochemistry: 1:50 -1:200 Immunofluorescence: 1:50 - 1:200

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 500-600 of human KU70.

Target Background

The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a singles-tranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.

Synonyms:XRCC6; CTC75; CTCBF; G22P1; KU70; ML8; TLAA; X -ray repair cross complementing 6

Storage

Store at -20℃. Avoid freeze / thaw cycles

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

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