Immunological Sciences

LDL Receptor (14L10) Rabbit Monoclonal Antibody

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Catalog Number:MABN13267
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human LDL Receptor
Reactivity:Human,Mouse
Applications:WB 1:500-1:2000,IHC 1:50-1:200,ICC/IF 1:20-1:100,FC 1:20-1:50
Molecular Weight:95kDa
Purification:Affinity purification
Form:Liquid
Synonyms:FH ; FHC ; LDL receptor; LDLCQ2; LDLR ; Low Density Lipoprotein Receptor; Low density lipoprotein receptor class A domain containing protein 3;

Applications

WB 1:500-1:2000,IHC 1:50-1:200,ICC/IF 1:20-1:100,FC 1:20-1:50

Immunogen

A synthetic peptide of human LDL Receptor

Target Background

Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. In case of HIV-1 infection, functions as a receptor for extracellular Tat in neurons, mediating its internalization in uninfected cells. Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits.

Synonyms:FH ; FHC ; LDL receptor; LDLCQ2; LDLR ; Low Density Lipoprotein Receptor; Low density lipoprotein receptor class A domain containing protein 3;

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

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