Immunological Sciences

Lin28 Rabbit Monoclonal Antibody

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Catalog Number:MABN86434
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human Lin28
Reactivity:Human
Applications:WB 1:1000-1:5000,ICC/IF 1:200-1:500
Molecular Weight:Calculated MW:23 kDa; Observed MW:28 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:CSDD1; LIN28; LIN-28; ZCCHC1; lin-28A

Applications

WB 1:1000-1:5000,ICC/IF 1:200-1:500

Immunogen

A synthetic peptide of human Lin28

Target Background

This gene encodes a LIN-28 family RNA-binding protein that acts as a posttranscriptional regulator of genes involved in developmental timing and self-renewal in embryonic stem cells. The encoded protein functions through direct interaction with target mRNAs and by disrupting the maturation of certain miRNAs involved in embryonic development. This protein prevents the terminal processing of the LET7 family of microRNAs which are major regulators of cellular growth and differentiation. Aberrant expression of this gene is associated with cancer progression in multiple tissues. [provided by RefSeq, Sep 2015]

Synonyms:CSDD1; LIN28; LIN-28; ZCCHC1; lin-28A

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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