Immunological Sciences

Lin28B Rabbit Monoclonal Antibody

No images available

Catalog Number:MABN87762
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:Recombinant protein of human Lin28B
Reactivity:Human
Applications:WB 1:500-1:2000,ICC/IF 1:100-1:200,FC 1:20-1:50,IP 1:20-1:50
Molecular Weight:Calculated MW:27 kDa; Observed MW:35 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:CSDD2

Applications

WB 1:500-1:2000,ICC/IF 1:100-1:200,FC 1:20-1:50,IP 1:20-1:50

Immunogen

Recombinant protein of human Lin28B

Target Background

The protein encoded by this gene belongs to the lin-28 family, which is characterized by the presence of a cold-shock domain and a pair of CCHC zinc finger domains. This gene is highly expressed in testis, fetal liver, placenta, and in primary human tumors and cancer cell lines. It is negatively regulated by microRNAs that target sites in the 3' UTR, and overexpression of this gene in primary tumors is linked to the repression of let-7 family of microRNAs and derepression of let-7 targets, which facilitates cellular transformation. [provided by RefSeq, Jun 2012]

Synonyms:CSDD2

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

No documents available.