Lipin 1 Rabbit Monoclonal Antibody

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Catalog Number:MABN87455
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human Lipin 1
Reactivity:Human
Applications:WB 1:1000-1:5000,IHC 1:50-1:100,ICC/IF 1:100-1:200,FC 1:10-1:100,IP 1:10-1:100
Molecular Weight:Calculated MW:99 kDa; Observed MW:130 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:PAP1

Applications

WB 1:1000-1:5000,IHC 1:50-1:100,ICC/IF 1:100-1:200,FC 1:10-1:100,IP 1:10-1:100

Immunogen

A synthetic peptide of human Lipin 1

Target Background

This gene encodes a magnesium-ion-dependent phosphatidic acid phosphohydrolase enzyme that catalyzes the penultimate step in triglyceride synthesis including the dephosphorylation of phosphatidic acid to yield diacylglycerol. Expression of this gene is required for adipocyte differentiation and it also functions as a nuclear transcriptional coactivator with some peroxisome proliferator-activated receptors to modulate expression of other genes involved in lipid metabolism. Mutations in this gene are associated with metabolic syndrome, type 2 diabetes, acute recurrent rhabdomyolysis, and autosomal recessive acute recurrent myoglobinuria (ARARM). This gene is also a candidate for several human lipodystrophy syndromes. [provided by RefSeq, Mar 2017]

Synonyms:PAP1

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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