LRP1 Mouse Monoclonal Antibody

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Catalog Number:MABN81556
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:Mouse IgG1
Clone:Monoclonal
Immunogen:Purified recombinant fragment of human LRP1 (AA: 20-155) expressed in E. Coli.
Reactivity:Human
Applications:IHC 1:200-1:1000,ICC 1:200-1:1000,ELISA 1:5000-1:20000
Molecular Weight:504kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:APR; LRP; A2MR; CD91; APOER; LRP1A; TGFBR5; IGFBP3R

Applications

IHC 1:200-1:1000,ICC 1:200-1:1000,ELISA 1:5000-1:20000

Immunogen

Purified recombinant fragment of human LRP1 (AA: 20-155) expressed in E. Coli.

Target Background

The protein encoded by this gene is an endocytic receptor involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells. In addition, the encoded protein is necessary for the A2M-mediated clearance of secreted amyloid precursor protein and beta-amyloid, the main component of amyloid plaques found in Alzheimer patients. Expression of this gene decreases with age and has been found to be lower than controls in brain tissue from Alzheimer patients.

Synonyms:APR; LRP; A2MR; CD91; APOER; LRP1A; TGFBR5; IGFBP3R

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide

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