LSP1 (8U19) Rabbit Monoclonal Antibody

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Catalog Number:MABN13465
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human LSP1
Reactivity:Human
Applications:WB 1:1000-1:5000,IHC 1:100-1:200,IF-P 1:100-1:200
Molecular Weight:37kDa
Purification:Affinity purification
Form:Liquid
Synonyms:Lymphocyte-specific protein 1; Protein pp52; 52 kDa phosphoprotein; Lymphocyte-specific antigen WP34; 47 kDa actin-binding protein;

Applications

WB 1:1000-1:5000,IHC 1:100-1:200,IF-P 1:100-1:200

Immunogen

A synthetic peptide of human LSP1

Target Background

LSP1 is a 52 kDa leukocyte-specific protein expressed in B cells, T cells, macrophages and neutrophils. The protein binds F-actin through its C-terminal actin-binding repeat and regulates cytoskeletal-related cellular movement such as polarization, chemotaxis and locomotion. LSP1 is a phospho-protein and has been identified as a major substrate of MAP kinase and PKC in lymphocytes and neutrophils. May play a role in mediating neutrophil activation and chemotaxis.

Synonyms:Lymphocyte-specific protein 1; Protein pp52; 52 kDa phosphoprotein; Lymphocyte-specific antigen WP34; 47 kDa actin-binding protein;

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.

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