Immunological Sciences

Lunatic Fringe Rabbit Monoclonal Antibody

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Catalog Number:MABN84116
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthesized peptide derived from human LFNG
Reactivity:Human,Mouse,Rat
Applications:WB 1:1000-1:2000,ICC 1:50-1:200
Molecular Weight:42 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:SCDO3;;LFNG

Applications

WB 1:1000-1:2000,ICC 1:50-1:200

Immunogen

A synthesized peptide derived from human LFNG

Target Background

Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. Modulates NOTCH1 activity by modifying O-fucose residues at specific EGF-like domains resulting in inhibition of NOTCH1 activation by JAG1 and enhancement of NOTCH1 activation by DLL1 via an increase in its binding to DLL1.

Synonyms:SCDO3;;LFNG

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

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