Immunological Sciences

MADCAM1 Rabbit Monoclonal Antibody

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Catalog Number:MABN84407
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthesized peptide derived from human MADCAM1
Reactivity:Human
Applications:WB 1:1000-1:2000
Molecular Weight:Calculated MW: 40 kDa ; Observed MW: 60 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:MACAM1; Madcam1;;MADCAM1

Applications

WB 1:1000-1:2000

Immunogen

A synthesized peptide derived from human MADCAM1

Target Background

Cell adhesion leukocyte receptor expressed by mucosal venules, helps to direct lymphocyte traffic into mucosal tissues including the Peyer patches and the intestinal lamina propria. It can bind both integrin alpha-4/beta-7 and L-selectin, regulating both the passage and retention of leukocytes. Isoform 2, lacking the mucin-like domain, may be specialized in supporting integrin alpha-4/beta-7-dependent adhesion strengthening, independent of L-selectin binding.

Synonyms:MACAM1; Madcam1;;MADCAM1

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

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