Immunological Sciences

Maf1 Rabbit Polyclonal Antibody

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Catalog Number:ABN13559
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:Synthesized peptide derived from Maf1 . at AA range: 110-190
Reactivity:Human,Mouse,Rat
Applications:IHC 1:100-1:300,ICC/IF 1:50-1:200,ELISA 1:10000-1:20000
Purification:Affinity purification
Form:Liquid
Synonyms:MAF1; Repressor of RNA polymerase III transcription MAF1 homolog

Applications

IHC 1:100-1:300,ICC/IF 1:50-1:200,ELISA 1:10000-1:20000

Immunogen

Synthesized peptide derived from Maf1 . at AA range: 110-190

Target Background

This gene encodes a protein that is similar to Maf1, a Saccharomyces cerevisiae protein highly conserved in eukaryotic cells. Yeast Maf1 is a negative effector of RNA polymerase III (Pol III). It responds to changes in the cellular environment and represses pol III transcription. Biochemical studies identified the initiation factor TFIIIB as a target for Maf1-dependent repression. [provided by RefSeq, Jul 2008],function:Mediator of diverse signals that repress RNA polymerase III transcription. Inhibits the de novo assembly of TFIIIB onto DNA.,similarity:Belongs to the MAF1 family.,subunit:Interacts with BRF2.,

Synonyms:MAF1; Repressor of RNA polymerase III transcription MAF1 homolog

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

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