MAGEA3 Rabbit Monoclonal Antibody

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Catalog Number:MABN02226
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:Recombinant protein of human MAGEA3
Reactivity:Human
Applications:WB 1:500-1:1000
Molecular Weight:Calculated MW: 35 kDa; Observed MW: 45 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:HIP8; HYPD; CT1.3; MAGE3; MAGEA6

Applications

WB 1:500-1:1000

Immunogen

Recombinant protein of human MAGEA3

Target Background

Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. May enhance ubiquitin ligase activity of TRIM28 and stimulate p53/TP53 ubiquitination by TRIM28. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. May play a role in embryonal development and tumor transformation or aspects of tumor progression. In vitro promotes cell viability in melanoma cell lines. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.

Synonyms:HIP8; HYPD; CT1.3; MAGE3; MAGEA6

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

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