Immunological Sciences

MAP3K13 (LZK) Mouse Monoclonal Antibody

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Catalog Number:MABN86117
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:Mouse IgM
Clone:Monoclonal
Immunogen:Purified His-tagged MAP3K13 protein fragment was used to produced this monoclonal antibody.
Reactivity:Human
Applications:WB 1:500-1:1000
Molecular Weight:108.3kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:Mitogen-activated protein kinase kinase kinase 13, Leucine zipper-bearing kinase, Mixed lineage kinase, MLK, MAP3K13 (<a href="http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=6852" target="_blank">HGNC:6852</a>)

Applications

WB 1:500-1:1000

Immunogen

Purified His-tagged MAP3K13 protein fragment was used to produced this monoclonal antibody.

Target Background

Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. Acts synergistically with PRDX3 to regulate the activation of NF-kappa-B in the cytosol. This activation is kinase-dependent and involves activating the IKK complex, the IKBKB-containing complex that phosphorylates inhibitors of NF-kappa-B.

Synonyms:Mitogen-activated protein kinase kinase kinase 13, Leucine zipper-bearing kinase, Mixed lineage kinase, MLK, MAP3K13 (<a href="http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=6852" target="_blank">HGNC:6852</a>)

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide.

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