Immunological Sciences

Mast Cell Tryptase (7Q2) Rabbit Monoclonal Antibody

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Catalog Number:MABN13658
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human Mast Cell Tryptase
Reactivity:Human
Applications:IHC 1:200-1:1000,IF-P 1:200-1:1000
Molecular Weight:31kDa
Purification:Affinity purification
Form:Liquid
Synonyms:TPS1; TPS2; TPSAB1; TPSB1; MCP 7 ; Mast cell protease 7; Tryptase alpha 1;

Applications

IHC 1:200-1:1000,IF-P 1:200-1:1000

Immunogen

A synthetic peptide of human Mast Cell Tryptase

Target Background

Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. Isoform 2 cleaves large substrates, such as fibronectin, more efficiently than isoform 1, but seems less efficient toward small substrates (PubMed:18854315).

Synonyms:TPS1; TPS2; TPSAB1; TPSB1; MCP 7 ; Mast cell protease 7; Tryptase alpha 1;

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

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