Immunological Sciences

MAX Rabbit Monoclonal Antibody

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Catalog Number:MABN87688
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:Recombinant protein of human MAX
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:2000,IP 1:20-1:50
Molecular Weight:Calculated MW:18 kDa; Observed MW:19-21 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:bHLHd4

Applications

WB 1:500-1:2000,IP 1:20-1:50

Immunogen

Recombinant protein of human MAX

Target Background

The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Mutations of this gene have been reported to be associated with hereditary pheochromocytoma. A pseudogene of this gene is located on the long arm of chromosome 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]

Synonyms:bHLHd4

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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