Immunological Sciences

MCM7 Rabbit Monoclonal Antibody

No images available

Catalog Number:MABN86453
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human MCM7
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:2000,IHC 1:50-1:100,ICC/IF 1:20-1:50,FC 1:20-1:50,IP 1:20-1:50
Molecular Weight:Calculated MW:81 kDa; Observed MW:81 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:MCM2; CDC47; P85MCM; P1CDC47; PNAS146; PPP1R104; P1.1-MCM3

Applications

WB 1:500-1:2000,IHC 1:50-1:100,ICC/IF 1:20-1:50,FC 1:20-1:50,IP 1:20-1:50

Immunogen

A synthetic peptide of human MCM7

Target Background

The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

Synonyms:MCM2; CDC47; P85MCM; P1CDC47; PNAS146; PPP1R104; P1.1-MCM3

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

No documents available.