MCP-1

No images available

Catalog Number:AB-80184
Size:100μg
Concentration:1mg/ml
Host:Rb
Isotype:IgG
Clone:POLY
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 24-99 of human MCP-1
Reactivity:Hu, Ms
Applications:Western Blot: 1:500 - 1:2000 Immunohistochemistry 1:100 - 1:200 Immunofluorescence: 1:50 - 1:100
Molecular Weight:11kDa
Purification:Aff. Pur.
Form:Liquid
Synonyms:CCL2;GDCF-2;HC11;HSMCR30;MCAF;MCP-1;MCP1;SCYA2 ;SMC-CF

Applications

Western Blot: 1:500 - 1:2000 Immunohistochemistry 1:100 - 1:200 Immunofluorescence: 1:50 - 1:100

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 24-99 of human MCP-1

Target Background

This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Chemokines are a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4

Synonyms:CCL2;GDCF-2;HC11;HSMCR30;MCAF;MCP-1;MCP1;SCYA2 ;SMC-CF

Storage

Store at -20℃. Avoid freeze / thaw cycles

Buffer

PBS with 0.02% sodium azide,50% glycerol,pH7.3

No documents available.