Immunological Sciences

Melatonin Receptor 1A Rabbit Polyclonal Antibody

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Catalog Number:ABN00432
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:The antiserum was produced against synthesized peptide derived from human MTR1A. AA range:191-240
Reactivity:Human,Mouse,Rat
Applications:ICC/IF 1:50-1:200,ELISA 1:5000-1:20000
Purification:Affinity Purification
Form:Liquid
Synonyms:MTNR1A; Melatonin receptor type 1A; Mel-1A-R; Mel1a receptor

Applications

ICC/IF 1:50-1:200,ELISA 1:5000-1:20000

Immunogen

The antiserum was produced against synthesized peptide derived from human MTR1A. AA range:191-240

Target Background

This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin.

Synonyms:MTNR1A; Melatonin receptor type 1A; Mel-1A-R; Mel1a receptor

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

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