MERTK Rabbit Monoclonal Antibody

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Catalog Number:MABN03084
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human MERTK
Reactivity:Human
Applications:WB 1:500-1:1000,IHC 1:50-1:100,IP 1:20-1:50
Molecular Weight:Calculated MW: 110 kDa; Observed MW: 210 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:MERTK; MER; Tyrosine-protein kinase Mer; Proto-oncogene c-Mer; Receptor tyrosine kinase MerTK

Applications

WB 1:500-1:1000,IHC 1:50-1:100,IP 1:20-1:50

Immunogen

A synthetic peptide of human MERTK

Target Background

MERTK signaling plays a role in various processes such as macrophage clearance of apoptotic cells, platelet aggregation, cytoskeleton reorganization and engulfment. Functions in the retinal pigment epithelium (RPE) as a regulator of rod outer segments fragments phagocytosis. Plays also an important role in inhibition of Toll-like receptors (TLRs)-mediated innate immune response by activating STAT1, which selectively induces production of suppressors of cytokine signaling SOCS1 and SOCS3.

Synonyms:MERTK; MER; Tyrosine-protein kinase Mer; Proto-oncogene c-Mer; Receptor tyrosine kinase MerTK

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

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