Immunological Sciences

Mesothelin Rabbit Monoclonal Antibody

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Catalog Number:MABN87815
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human Mesothelin
Reactivity:Human
Applications:WB 1:1000-1:5000,IHC 1:200-1:1000,IP 1:10-1:100
Molecular Weight:Calculated MW:69 kDa; Observed MW:46-48, 70 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:MPF; SMRP

Applications

WB 1:1000-1:5000,IHC 1:200-1:1000,IP 1:10-1:100

Immunogen

A synthetic peptide of human Mesothelin

Target Background

This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016]

Synonyms:MPF; SMRP

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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