Metabotropic Glutamate Receptor 5 Rabbit Monoclonal Antibody

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Catalog Number:MABN86676
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human Metabotropic Glutamate Receptor 5
Reactivity:Human,Mouse,Rat
Applications:WB 1:1000-1:5000,IHC 1:200-1:500,FC 1:10-1:100
Molecular Weight:Calculated MW:132 kDa; Observed MW:150,300 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:mGlu5; GPRC1E; MGLUR5; PPP1R86

Applications

WB 1:1000-1:5000,IHC 1:200-1:500,FC 1:10-1:100

Immunogen

A synthetic peptide of human Metabotropic Glutamate Receptor 5

Target Background

This gene encodes a member of the G-protein coupled receptor 3 protein family. The encoded protein is a metabatropic glutamate receptor, whose signaling activates a phosphatidylinositol-calcium second messenger system. This protein may be involved in the regulation of neural network activity and synaptic plasticity. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. A pseudogene of this gene has been defined on chromosome 11. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]

Synonyms:mGlu5; GPRC1E; MGLUR5; PPP1R86

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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