MGMT Mouse Monoclonal Antibody

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Catalog Number:MABN85997
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:Mouse IgG1
Clone:Monoclonal
Immunogen:This MGMT antibody is generated from a mouse immunized with a recombinant protein.
Reactivity:Human, Mouse, Rat
Applications:WB 1:1000-1:2000,FC 1:25-1:50
Molecular Weight:21.6kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:Methylated-DNA--protein-cysteine methyltransferase, 6-O-methylguanine-DNA methyltransferase, MGMT, O-6-methylguanine-DNA-alkyltransferase, MGMT

Applications

WB 1:1000-1:2000,FC 1:25-1:50

Immunogen

This MGMT antibody is generated from a mouse immunized with a recombinant protein.

Target Background

Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

Synonyms:Methylated-DNA--protein-cysteine methyltransferase, 6-O-methylguanine-DNA methyltransferase, MGMT, O-6-methylguanine-DNA-alkyltransferase, MGMT

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide.

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