MGMT Rabbit Monoclonal Antibody

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Catalog Number:MABN03086
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human MGMT
Reactivity:Human
Applications:WB 1:500-1:1000,IP 1:20-1:50
Molecular Weight:Calculated MW: 22 kDa; Observed MW: 22 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:Methylated-DNA--protein-cysteine methyltransferase

Applications

WB 1:500-1:1000,IP 1:20-1:50

Immunogen

A synthetic peptide of human MGMT

Target Background

MGMT (O-6-methylguanine-DNA methyltransferase) is a DNA repair enzyme that participates in a suicide reaction that specifically removes methyl or alkyl groups from the O(6) position of guanine, restoring guanine to its normal form without causing DNA breaks. MGMT protects cells from alkylating toxins, and is an important factor in drug resistance to alkylating therapeutic agents.

Synonyms:Methylated-DNA--protein-cysteine methyltransferase

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

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