Immunological Sciences

MIB1 Mouse Monoclonal Antibody

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Catalog Number:MABN81758
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:Mouse IgG1
Clone:Monoclonal
Immunogen:Purified recombinant fragment of human MIB1 (AA: 6-221) expressed in E. Coli.
Reactivity:Human,Monkey
Applications:WB 1:500-1:2000,ELISA 1:5000-1:20000,FC 1:200-1:400
Molecular Weight:110kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:MIB; DIP1; ZZZ6; DIP-1; LVNC7; ZZANK2

Applications

WB 1:500-1:2000,ELISA 1:5000-1:20000,FC 1:200-1:400

Immunogen

Purified recombinant fragment of human MIB1 (AA: 6-221) expressed in E. Coli.

Target Background

This gene encodes a protein containing multiple ankyrin repeats and RING finger domains that functions as an E3 ubiquitin ligase. The encoded protein positively regulates Notch signaling by ubiquitinating the Notch receptors, thereby facilitating their endocytosis. This protein may also promote the ubiquitination and degradation of death-associated protein kinase 1 (DAPK1).

Synonyms:MIB; DIP1; ZZZ6; DIP-1; LVNC7; ZZANK2

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide

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