Immunological Sciences

MiTF Rabbit Monoclonal Antibody

No images available

Catalog Number:MABN21582
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG,Kappa
Clone:Monoclonal
Reactivity:Human,Mouse,Rat,
Applications:WB 1:1000-1:5000,IHC 1:200-1:500,ICC/IF 1:200-1:1000,ELISA 1:5000-1:20000,IP 1:50-1:200
Molecular Weight:CalcuLated MW:58kD;Observed MW:58kD
Purification:Protein A
Form:Liquid
Synonyms:MITF;BHLHE32;Microphthalmia-associated transcription factor;Class E basic helix-loop-helix protein 32;bHLHe32

Applications

WB 1:1000-1:5000,IHC 1:200-1:500,ICC/IF 1:200-1:1000,ELISA 1:5000-1:20000,IP 1:50-1:200

Target Background

Cell localization:Nuclear.This gene encodes a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],

Synonyms:MITF;BHLHE32;Microphthalmia-associated transcription factor;Class E basic helix-loop-helix protein 32;bHLHe32

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

No documents available.