MLH1 Rabbit Monoclonal Antibody

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Catalog Number:MABN85174
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human MLH1
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:1000,ICC 1:50-1:200,IP 1:10-1:20
Molecular Weight:Calculated MW: 85 kDa; Observed MW: 85 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:MLH1; COCA2; DNA mismatch repair protein Mlh1; MutL protein homolog 1

Applications

WB 1:500-1:1000,ICC 1:50-1:200,IP 1:10-1:20

Immunogen

A synthetic peptide of human MLH1

Target Background

This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Alternatively spliced transcript variants encoding different isoforms have been described, but their full-length natures have not been determined.

Synonyms:MLH1; COCA2; DNA mismatch repair protein Mlh1; MutL protein homolog 1

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.

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