MLKL Rabbit Monoclonal antibody

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Catalog Number:MABN04091
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide corresponding to target protein
Reactivity:Human
Applications:WB 1:500-1:1000
Molecular Weight:Calculated MW: 54 kDa; Observed MW: 54 kDa
Purification:Affinity Purified
Form:Liquid
Synonyms:MLKL

Applications

WB 1:500-1:1000

Immunogen

A synthetic peptide corresponding to target protein

Target Background

Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity.

Synonyms:MLKL

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

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