MLKL Rabbit Monoclonal Antibody

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Catalog Number:MABN83772
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthesized peptide derived from human MLKL
Reactivity:Human
Applications:WB 1:1000-1:2000,IHC 1:100-1:200
Molecular Weight:54 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:Mixed lineage kinase domain-like protein; hMLKL; ;MLKL

Applications

WB 1:1000-1:2000,IHC 1:100-1:200

Immunogen

A synthesized peptide derived from human MLKL

Target Background

Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process.Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage.

Synonyms:Mixed lineage kinase domain-like protein; hMLKL; ;MLKL

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

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