Immunological Sciences

MLL3 Mouse Monoclonal Antibody

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Catalog Number:MABN86043
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:Mouse IgG1
Clone:Monoclonal
Immunogen:This MLL3 antibody is generated from a mouse immunized with a recombinant protein of human MLL3.
Reactivity:Human, Mouse
Applications:WB 1:1000-1:2000
Molecular Weight:541.4kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:Histone-lysine N-methyltransferase 2C, Lysine N-methyltransferase 2C, 2.1.1.43, Homologous to ALR protein, Myeloid/lymphoid or mixed-lineage leukemia protein 3, KMT2C, HALR, KIAA1506, MLL3

Applications

WB 1:1000-1:2000

Immunogen

This MLL3 antibody is generated from a mouse immunized with a recombinant protein of human MLL3.

Target Background

Histone methyltransferase. Methylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Central component of the MLL2/3 complex, a coactivator complex of nuclear receptors, involved in transcriptional coactivation. KMT2C/MLL3 may be a catalytic subunit of this complex. May be involved in leukemogenesis and developmental disorder.

Synonyms:Histone-lysine N-methyltransferase 2C, Lysine N-methyltransferase 2C, 2.1.1.43, Homologous to ALR protein, Myeloid/lymphoid or mixed-lineage leukemia protein 3, KMT2C, HALR, KIAA1506, MLL3

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in TBS with 0.05% sodium azide.

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