Immunological Sciences

MOF Rabbit Polyclonal Antibody

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Catalog Number:ABN14023
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:The antiserum was produced against synthesized peptide derived from human MYST1. AA range:101-150
Reactivity:Human,Mouse,Rat
Applications:IHC 1:100-1:300,ICC/IF 1:50-1:200,ELISA 1:5000-1:20000
Purification:Affinity purification
Form:Liquid
Synonyms:KAT8; MOF; MYST1; PP7073; Histone acetyltransferase KAT8; Lysine acetyltransferase 8; MOZ; YBF2/SAS3, SAS2 and TIP60 protein 1; MYST-1; hMOF

Applications

IHC 1:100-1:300,ICC/IF 1:50-1:200,ELISA 1:5000-1:20000

Immunogen

The antiserum was produced against synthesized peptide derived from human MYST1. AA range:101-150

Target Background

This gene encodes a member of the MYST histone acetylase protein family. The encoded protein has a characteristic MYST domain containing an acetyl-CoA-binding site, a chromodomain typical of proteins which bind histones, and a C2HC-type zinc finger. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012],catalytic activity:Acetyl-CoA + histone = CoA + acetylhistone.,function:Histone acetyltransferase which may be involved in transcriptional activation. May influence the function of ATM.,similarity:Belongs to the MYST (SAS/MOZ) family.,similarity:Contains 1 C2HC-type zinc finger.,similarity:Contains 1 chromo domain.,subunit:Component of a multisubunit histone acetyltransferase complex (MSL) at least composed of the MOF/MYST1, MSL1/hampin, MSL2L1 and MSL3L1. Interacts with the chromodomain of MORF4L1/MRG15. Interacts with ATM through the chromodomain.,

Synonyms:KAT8; MOF; MYST1; PP7073; Histone acetyltransferase KAT8; Lysine acetyltransferase 8; MOZ; YBF2/SAS3, SAS2 and TIP60 protein 1; MYST-1; hMOF

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

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