Immunological Sciences

MOT4 Rabbit Polyclonal Antibody

No images available

Catalog Number:ABN14039
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:Synthesized peptide derived from human MOT4 Polyclonal
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:2000,IHC 1:50-1:300,ELISA 1:2000-1:20000
Molecular Weight:50kDa
Purification:Affinity purification
Form:Liquid
Synonyms:Monocarboxylate transporter 4 (MCT 4) (Solute carrier family 16 member 3)

Applications

WB 1:500-1:2000,IHC 1:50-1:300,ELISA 1:2000-1:20000

Immunogen

Synthesized peptide derived from human MOT4 Polyclonal

Target Background

Lactic acid and pyruvate transport across plasma membranes is catalyzed by members of the proton-linked monocarboxylate transporter (MCT) family, which has been designated solute carrier family-16. Each MCT appears to have slightly different substrate and inhibitor specificities and transport kinetics, which are related to the metabolic requirements of the tissues in which it is found. The MCTs, which include MCT1 (SLC16A1; MIM 600682) and MCT2 (SLC16A7; MIM 603654), are characterized by 12 predicted transmembrane domains (Price et al., 1998 [PubMed 9425115]).[supplied by OMIM, Mar 2008],function:Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate.,similarity:Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.,tissue specificity:Highly expressed in skeletal muscle.,

Synonyms:Monocarboxylate transporter 4 (MCT 4) (Solute carrier family 16 member 3)

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

No documents available.