Mouse TUG Mouse Monoclonal Antibody

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Catalog Number:MABN80530
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:Mouse IgG1
Clone:Monoclonal
Immunogen:Purified recombinant fragment of TUG expressed in E. Coli.
Reactivity:Mouse
Applications:WB 1:500-1:2000,ELISA 1:5000-1:20000
Molecular Weight:31kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:ASPCR1, ASPL, ASPS, RCC17, TUG, UBXD9, UBXN9

Applications

WB 1:500-1:2000,ELISA 1:5000-1:20000

Immunogen

Purified recombinant fragment of TUG expressed in E. Coli.

Target Background

The TUG protein contains a UBX domain, for GLUT4. In truncated form, TUG acts in a dominant-negative manner to inhibit insulin-stimulated GLUT4 redistribution in Chinese hamster ovary cells and 3T3-L1 adipocytes. Full-length TUG forms a complex specifically with GLUT4. In 3T3-L1 adipocytes, this complex is present in unstimulated cells and is largely disassembled by insulin. Endogenous TUG is localized with the insulin-mobilizable pool of GLUT4 in unstimulated 3T3-L1 adipocytes, and is not mobilized to the plasma membrane by insulin.

Synonyms:ASPCR1, ASPL, ASPS, RCC17, TUG, UBXD9, UBXN9

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Ascitic fluid containing 0.03% sodium azide.

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