Immunological Sciences

MRP1 Rabbit Monoclonal Antibody

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Catalog Number:MABN87061
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human MRP1
Reactivity:Human
Applications:WB 1:500-1:2000,IHC 1:500-1:2000,ICC/IF 1:100-1:200
Molecular Weight:Calculated MW:172 kDa; Observed MW:170-220 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:MRP; ABCC; GS-X; MRP1; ABC29

Applications

WB 1:500-1:2000,IHC 1:500-1:2000,ICC/IF 1:100-1:200

Immunogen

A synthetic peptide of human MRP1

Target Background

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternatively spliced variants of this gene have been described but their full-length nature is unknown. [provided by RefSeq, Apr 2012]

Synonyms:MRP; ABCC; GS-X; MRP1; ABC29

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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