Immunological Sciences

MSI2 Mouse Monoclonal Antibody

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Catalog Number:MABN80959
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:Mouse IgG1
Clone:Monoclonal
Immunogen:Purified recombinant fragment of human MSI2 expressed in E. Coli.
Reactivity:Human
Applications:WB 1:500-1:2000,IHC 1:200-1:1000,ELISA 1:5000-1:20000
Molecular Weight:35kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:MSI2H; MGC3245; FLJ36569; MSI2

Applications

WB 1:500-1:2000,IHC 1:200-1:1000,ELISA 1:5000-1:20000

Immunogen

Purified recombinant fragment of human MSI2 expressed in E. Coli.

Target Background

Msi2 (musashi homolog 2), also known as MSI2H, is a 328 amino acid protein that localizes to the cytoplasm and contains two RRM (RNA recognition motif) domains. Expressed ubiquitously at low levels, Msi2 functions as an RNA binding protein that, by regulating the expression of target mRNAs, is thought to play a role in the proliferation and maintenance of stem cells within the central nervous system. Msi2 is subject to posttranslational phosphorylation and is upregulated in response to brain injury, suggesting a role in healing and brain tissue regeneration. Chromosomal aberrations involving the Msi2 gene are associated with the progression of chronic myeloid leukemia. Multiple isoforms of Msi2 exist due to alternative splicing events.Tissue specificity: Ubiquitous; detected at low levels.

Synonyms:MSI2H; MGC3245; FLJ36569; MSI2

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide.

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