mTOR (1L6) Rabbit Monoclonal Antibody

No images available

Catalog Number:MABN14217
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human mTOR
Reactivity:Human,Mouse,Rat
Applications:WB 1:1000-1:2000
Molecular Weight:289kDa
Purification:Affinity purification
Form:Liquid
Synonyms:FRAP; FRAP1; FRAP2; RAFT1; Rapamycin target protein; kinase mTOR;

Applications

WB 1:1000-1:2000

Immunogen

A synthetic peptide of human mTOR

Target Background

An atypical kinase belonging to the PIKK family of kinases. Controls cell growth through protein synthesis regulation. Downstream of PI3K/Akt pathway and required for cell survival. Acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. Serine/threonine protein kinase which is a central regulator of cellular metabolism, growth and survival in response to hormones, growth factors, nutrients, energy and stress signals

Synonyms:FRAP; FRAP1; FRAP2; RAFT1; Rapamycin target protein; kinase mTOR;

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

No documents available.