Mucin 1
Western Blot analysis of NIH-3T3 cells using Mucin 1 Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
| Catalog Number: | ABE4347 |
| Conjugate: | Unconjugated |
| Size: | 100ug |
| Concentration: | 1mg/ml |
| Host: | Rb |
| Isotype: | IgG |
| Clone: | POLY |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the Internal region of human MUC1. AA range:1021-1070 |
| Reactivity: | Hu,Ms,Rt |
| Applications: | WB,IHC,IF,ELISA |
| Molecular Weight: | 122kD |
| Purification: | Affinity Purified |
| Form: | Liquid |
This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate sp
Applications
WB,IHC,IF,ELISA
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human MUC1. AA range:1021-1070
