Immunological Sciences

Munc 13-4 Rabbit Monoclonal Antibody

No images available

Catalog Number:MABN87130
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human Munc 13-4
Reactivity:Human,Mouse
Applications:WB 1:1000-1:5000,FC 1:10-1:100
Molecular Weight:Calculated MW:123 kDa; Observed MW:123 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:FHL3; HLH3; HPLH3; Munc13-4

Applications

WB 1:1000-1:5000,FC 1:10-1:100

Immunogen

A synthetic peptide of human Munc 13-4

Target Background

This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder. [provided by RefSeq, Jul 2008]

Synonyms:FHL3; HLH3; HPLH3; Munc13-4

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

No documents available.