Immunological Sciences

MxB Rabbit Polyclonal Antibody

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Catalog Number:ABN14254
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:Synthesized peptide derived from the Internal region of human MxB.
Reactivity:Human,Rat,Mouse
Applications:WB 1:500-1:2000,IHC 1:50-1:300
Molecular Weight:82kDa
Purification:Affinity purification
Form:Liquid
Synonyms:MX2; Interferon-induced GTP-binding protein Mx2; Interferon-regulated resistance GTP-binding protein MxB; Myxovirus resistance protein 2; p78-related protein

Applications

WB 1:500-1:2000,IHC 1:50-1:300

Immunogen

Synthesized peptide derived from the Internal region of human MxB.

Target Background

The protein encoded by this gene has a nuclear and a cytoplasmic form and is a member of both the dynamin family and the family of large GTPases. The nuclear form is localized in a granular pattern in the heterochromatin region beneath the nuclear envelope. A nuclear localization signal (NLS) is present at the amino terminal end of the nuclear form but is lacking in the cytoplasmic form due to use of an alternate translation start codon. This protein is upregulated by interferon-alpha but does not contain the antiviral activity of a similar myxovirus resistance protein 1. [provided by RefSeq, Jul 2008],induction:By interferons.,similarity:Belongs to the dynamin family.,similarity:Contains 1 GED domain.,

Synonyms:MX2; Interferon-induced GTP-binding protein Mx2; Interferon-regulated resistance GTP-binding protein MxB; Myxovirus resistance protein 2; p78-related protein

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

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